rs147358466
This is a regulatory region variant variant in the DLGAP2 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
breast cancer
Hsu YC et al. “The largest genome-wide association study for breast cancer in Taiwanese Han population.” Breast Cancer Research and Treatment 203(2):291-306 (2024)
Allele A
OR 1.49
p 6.0e-12
N 12,480
Large GWAS
East Asian
About DLGAP2
The product of this gene is a membrane-associated protein that may play a role in synapse organization and signalling in neuronal cells. This gene is biallelically expressed in the brain, however, only the paternal allele is expressed in the testis (PMID:18055845). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2014]
View all DLGAP2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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