rs1476455

This is a intron variant variant in the ELAPOR2 gene.

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Research that mentions this SNP (1)

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Association between type‐three metabotropic glutamate receptor gene (GRM3) variants and symptom presentation in treatment refractory schizophrenia
AssociationN=95Jeffrey R. Bishop et al.(2011)· Human Psychopharmacology: Clinical and Experimental

This candidate gene association study examined 95 treatment-refractory schizophrenia patients genotyped for seven GRM3 markers. Two SNPs (rs1989796 and rs1476455) at the 3' end of the gene were significantly associated with global psychosis symptoms measured by BPRS total scores (rs1476455: CC genotype 55.1±10.4 vs A-carriers 48.3±9.2, F=7.6, p=0.0071; rs1989796: CC genotype 50.1±5.7 vs T-carriers 55.8±10.5, F=7.1, p=0.0091), but not with negative symptoms.

Traits studied:Antipsychotic responseGlobal psychosis symptoms (BPRS)Negative symptoms (SANS)Schizophrenia - treatment refractory symptoms
PubMedDOIMetascience Observatory

About ELAPOR2

Predicted to enable BMP receptor binding activity. Predicted to be involved in negative regulation of nervous system development; positive regulation of BMP signaling pathway; and positive regulation of epidermis development. Predicted to be located in plasma membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all ELAPOR2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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