rs147967138
This is a upstream gene variant variant in the MAGI2 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
pulse pressure measurement, depressive symptom measurement
Lee S et al. “Large-scale blood pressure GWAS accounting for gene-depression interactions in 564,680 individuals from diverse populations.” Hgg Advances 7(2):100566 (2026)
Allele A
OR 5.12
p 3.0e-8
N 39,389
Large GWAS
East Asian, South Asian
About MAGI2
The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq, Jul 2008]
View all MAGI2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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