rs148520164

This is a downstream gene variant variant in the MT1M gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Tics, Stuttering

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 2.90
p 3.0e-11
N 572,345
Major Consortium StudyLarge GWAS
multi-ancestry

About MT1M

This gene encodes a member of the metallothionein superfamily, type 1 family. Metallothioneins have a high content of cysteine residues that bind various heavy metals. These genes are transcriptionally regulated by both heavy metals and glucocorticoids. [provided by RefSeq, Oct 2011]

View all MT1M variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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