rs149066790
This is a regulatory region variant variant in the SPAG7 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
sphingomyelin measurement
Tabassum R et al. “Genetic architecture of human plasma lipidome and its link to cardiovascular disease.” Nature Communications 10(1):4329 (2019)
Allele A
OR 0.89
p 5.0e-20
N 2,045
Large GWAS
European
stearoyl sphingomyelin (d18:1/18:0) measurement
Yin X et al. “Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.” Nature Communications 13(1):1644 (2022)
Allele A
OR 0.40
p 6.0e-16
N 6,136
Large GWAS
European
About SPAG7
Predicted to enable nucleic acid binding activity. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
View all SPAG7 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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