rs149187226
This is a intron variant variant in the RIN3 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Sepsis, mortality
Butler-Laporte G et al. “Elevated body mass index is associated with an increased risk of infectious disease admissions and mortality: a mendelian randomization study.” Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases (2020)
Allele G
OR 0.35
p 4.0e-8
N 2,037
Large GWAS
European
About RIN3
Summary: This protein encoded by this gene is a member of the RIN family of Ras interaction-interference proteins, which are binding partners to the RAB5 small GTPases. The protein functions as a guanine nucleotide exchange for RAB5B and RAB31. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
View all RIN3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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