rs149403252
This is a intron variant variant in the ERC2 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
blood glucose amount, response to metformin
Li JH et al. “Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH.” Diabetologia 66(7):1260-1272 (2023)
Allele T
OR 1.30
p 2.0e-9
N 809
Small GWAS
African American or Afro-Caribbean, European, Hispanic or Latin American, Asian unspecified, NR
About ERC2
This gene encodes a protein that belongs to the Rab3-interacting molecule (RIM)-binding protein family. Members of this protein family form part of the cytomatrix at the active zone (CAZ) complex and function as regulators of neurotransmitter release. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
View all ERC2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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