rs149982219

This is a protein-altering variant in the IGSF11 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Hodgkins lymphoma

Osman Y et al. “Functional multigenic variations associated with hodgkin lymphoma.” International Journal of Laboratory Hematology 43(6):1472-1482 (2021)

Allele A

OR —

β 0.032

p 5.0e-11

N 97

Small GWAS

Greater Middle Eastern (Middle Eastern, North African or Persian)

About IGSF11

IGSF11 is an immunoglobulin (Ig) superfamily member that is preferentially expressed in brain and testis. It shares significant homology with coxsackievirus and adenovirus receptor (CXADR; MIM 602621) and endothelial cell-selective adhesion molecule (ESAM).[supplied by OMIM, Apr 2005]

View all IGSF11 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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