rs150112597
This is a protein-altering variant in the HOXD1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
glucose-dependent insulinotropic peptide measurement, glucose tolerance test
Almgren P et al. “Genetic determinants of circulating GIP and GLP-1 concentrations.” Jci Insight 2(21) (2017)
Allele C
OR 0.28
p 2.0e-8
N 3,344
Large GWAS
European
About HOXD1
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. This nuclear protein functions as a sequence-specific transcription factor that is involved in differentiation and limb development. Mutations in this gene have been associated with severe developmental defects on the anterior-posterior (a-p) limb axis. [provided by RefSeq, Jul 2008]
View all HOXD1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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