rs150539196
This is a synonymous variant in the ZBTB10 gene — it does not change the protein's amino acid sequence.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
sex hormone-binding globulin measurement
Harrison S et al. “Testosterone and socioeconomic position: Mendelian randomization in 306,248 men and women in UK Biobank.” Science Advances 7(31) (2021)
Allele G
OR 3.85
p 4.0e-18
N 104,632
Major Consortium StudyLarge GWAS
European
testosterone measurement
Ruth KS et al. “Using human genetics to understand the disease impacts of testosterone in men and women.” Nature Medicine 26(2):252-258 (2020)
Allele G
OR 0.02
p 4.0e-10
N 425,097
Large GWAS
European
Harrison S et al. “Testosterone and socioeconomic position: Mendelian randomization in 306,248 men and women in UK Biobank.” Science Advances 7(31) (2021)
Allele G
OR 0.30
p 4.0e-10
N 148,248
Major Consortium StudyLarge GWAS
European
About ZBTB10
Enables telomeric DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Located in chromosome, telomeric region and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
View all ZBTB10 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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