rs150760389

This variant is located in the KRT39 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Hodgkins lymphoma

Osman Y et al. “Functional multigenic variations associated with hodgkin lymphoma.” International Journal of Laboratory Hematology 43(6):1472-1482 (2021)

Allele T

OR —

β 0.046

p 4.0e-11

N 97

Small GWAS

Greater Middle Eastern (Middle Eastern, North African or Persian)

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ClinVar annotation

Uncertain Significance★☆☆☆

1 submitter

not specified

View on ClinVar →

About KRT39

This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]

View all KRT39 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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