rs150947563

This is a intron variant variant in the ZBTB46 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

prostate carcinoma

Wang A et al. “Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants.” Nature Genetics 55(12):2065-2074 (2023)

Allele C

OR 1.47

p 3.0e-10

N 80,999

Large GWAS

African American or Afro-Caribbean

Chen F et al. “Evidence of Novel Susceptibility Variants for Prostate Cancer and a Multiancestry Polygenic Risk Score Associated with Aggressive Disease in Men of African Ancestry.” European Urology 84(1):13-21 (2023)

Allele C

OR 1.47

p 3.0e-10

N 80,998

Large GWAS

African unspecified

About ZBTB46

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Involved in regulation of transcription by RNA polymerase II. Predicted to be located in chromatin. [provided by Alliance of Genome Resources, Jul 2025]

View all ZBTB46 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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