rs1537377
This is a regulatory region variant variant.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
endometriosis
Shigesi N et al. “The phenotypic and genetic association between endometriosis and immunological diseases.” Human Reproduction (oxford, England) 40(6):1195-1209 (2025)
Allele T
OR 0.03
p 1.0e-18
N 217,530
Large GWAS
European
Sapkota Y et al. “Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism.” Nature Communications 8:15539 (2017)
Allele T
OR 1.09
p 1.0e-10
N 208,903
Meta-analysisLarge GWAS
multi-ancestry
Nyholt DR et al. “Genome-wide association meta-analysis identifies new endometriosis risk loci.” Nature Genetics 44(12):1355-9 (2012)
Allele T
OR 1.15
p 2.0e-9
N 13,997
Meta-analysisLarge GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…