rs153916

This variant is located in the SPATA9 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

chronic obstructive pulmonary disease

Sakornsakolpat P et al. “Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.” Nature Genetics 51(3):494-505 (2019)

Allele T

OR 1.06

p 6.0e-10

N 257,811

Large GWAS

European, East Asian, African American or Afro-Caribbean, Hispanic or Latin American, NR

FEV/FVC ratio, pulmonary function measurement

Soler Artigas M et al. “Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.” Nature Genetics 43(11):1082-90 (2011)

Allele T

OR 0.03

p 2.0e-8

N 48,201

Large GWAS

European

About SPATA9

Predicted to be involved in cell differentiation and spermatogenesis. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all SPATA9 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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