rs1550976
This is a intron variant variant in the NTM gene.
▶Research that mentions this SNP (1)
▶Variants in several genomic regions associated with asperger disorderAssociationN=860Salyakina D. et al.(2010)· Autism Research
Genome-wide association study in 124 families with Asperger disorder (discovery) and 110 families (validation) identified novel susceptibility loci on 5q21.1 (P = 9.7 × 10⁻⁷, rs4703129) and 15q22.1-q22.2 (P = 7.3 × 10⁻⁶, rs4775101) associated with Asperger disorder. The study confirmed three regions previously linked to Asperger disorder in Finnish families (3p14.2, 3q25-26, 3p23) and identified 26 candidate genes, suggesting that Asperger disorder shares both ASD-related genetic risk factors as well as unique genetic risk factors.
About NTM
This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. This gene is closely linked to a related family member, opioid binding protein/cell adhesion molecule-like (OPCML), on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009]
View all NTM variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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