rs1561288

This is a intron variant variant in the EFR3B gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body mass index

Koskeridis F et al. “Pleiotropic genetic architecture and novel loci for C-reactive protein levels.” Nature Communications 13(1):6939 (2022)

Allele T

OR 0.02

p 9.0e-24

N 694,649

Large GWAS

European

Graff M et al. “Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.” Human Molecular Genetics 22(17):3597-607 (2013)

Allele T

OR 0.06

p 5.0e-8

N 13,627

Large GWAS

European

About EFR3B

Involved in phosphatidylinositol phosphate biosynthetic process and protein localization to plasma membrane. Located in actin cytoskeleton; cytosol; and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all EFR3B variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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