rs1582874

This variant is located in the ZBTB38 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

prostate specific antigen amount

Kachuri L et al. “Genetically adjusted PSA levels for prostate cancer screening.” Nature Medicine 29(6):1412-1423 (2023)

Allele C

OR 0.03

p 1.0e-16

N 95,768

Large GWAS

multi-ancestry

mathematical ability

Lee JJ et al. “Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.” Nature Genetics 50(8):1112-1121 (2018)

Allele T

OR 0.01

p 7.0e-10

N 811,539

Large GWAS

European

About ZBTB38

The protein encoded by this gene is a zinc finger transcriptional activator that binds methylated DNA. The encoded protein can form homodimers or heterodimers through the zinc finger domains. In mouse, inhibition of this protein has been associated with apoptosis in some cell types. [provided by RefSeq, Jun 2010]

View all ZBTB38 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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