rs1599914790

This variant is located in the STK11 gene.

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ClinVar annotation

Uncertain Significance★★★☆
4 submitters3 publications

Peutz-Jeghers syndrome; Hereditary cancer-predisposing syndrome

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About STK11

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with the autosomal dominant Peutz-Jeghers syndrome, as well as with skin, pancreatic, and testicular cancers. [provided by RefSeq, May 2022]

View all STK11 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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