rs160459
▶GWAS Catalog Trait Associations (8)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (8)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
brain connectivity attribute
Sha Z et al. “Genetic architecture of the white matter connectome of the human brain.” Science Advances 9(7):eadd2870 (2023)
Allele A
OR 15.46
p 7.0e-54
N 30,810
Large GWAS
European
hippocampal formation volume
van der Meer D et al. “Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes.” Molecular Psychiatry 25(11):3053-3065 (2020)
Allele C
OR 7.45
p 2.0e-17
N 21,297
Large GWAS
European
cortical thickness
Grasby KL et al. “The genetic architecture of the human cerebral cortex.” Science (new York, N.y.) 367(6484) (2020)
Allele A
OR 0.01
p 1.0e-16
N 33,992
Large GWAS
European
brain attribute
Sha Z et al. “The genetic architecture of structural left-right asymmetry of the human brain.” Nature Human Behaviour 5(9):1226-1239 (2021)
Allele C
OR —
p 5.0e-12
N 32,256
Large GWAS
European
hippocampal CA1 volume
van der Meer D et al. “Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes.” Molecular Psychiatry 25(11):3053-3065 (2020)
Allele C
OR 2.98
p 2.0e-10
N 21,297
Large GWAS
European
hippocampal volume
Liu N et al. “Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes.” Nature Genetics 55(7):1126-1137 (2023)
Allele C
OR 0.05
p 3.0e-10
N 38,977
Large GWAS
European, East Asian
granule cell layer dentate gyrus volume
van der Meer D et al. “Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes.” Molecular Psychiatry 25(11):3053-3065 (2020)
Allele C
OR 1.53
p 2.0e-9
N 21,297
Large GWAS
European
amygdala volume
Ji Y et al. “Cross-ancestry and sex-stratified genome-wide association analyses of amygdala and subnucleus volumes.” Nature Genetics 57(4):839-850 (2025)
Allele C
OR 0.04
p 1.0e-10
N 35,474
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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