rs1620977
▶GWAS Catalog Trait Associations (9)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (9)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
insomnia
Watanabe K et al. “Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways.” Nature Genetics 54(8):1125-1132 (2022)
Allele A
OR 0.01
p 1.0e-31
N 2,365,010
Meta-analysisLarge GWAS
European
insomnia measurement
Jansen PR et al. “Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways.” Nature Genetics 51(3):394-403 (2019)
Allele A
OR 1.05
p 2.0e-14
N 1,331,010
Large GWAS
European
bipolar disorder, body mass index
Pisanu C et al. “Evidence that genes involved in hedgehog signaling are associated with both bipolar disorder and high BMI.” Translational Psychiatry 9(1):315 (2019)
Allele A
OR 0.02
p 9.0e-13
N 373,864
Large GWAS
European
intelligence
Davies G et al. “Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.” Nature Communications 9(1):2098 (2018)
Allele A
OR 6.66
p 3.0e-11
N 300,486
Large GWAS
European
fat intake measurement
Merino J et al. “Genetic analysis of dietary intake identifies new loci and functional links with metabolic traits.” Nature Human Behaviour 6(1):155-163 (2022)
Allele A
OR 0.12
p 3.0e-9
N 282,271
Large GWAS
European
autism spectrum disorder, major depressive disorder
Grove J et al. “Identification of common genetic risk variants for autism spectrum disorder.” Nature Genetics 51(3):431-444 (2019)
Allele A
OR 0.06
p 7.0e-9
N 470,365
Large GWAS
European
endometriosis, major depressive disorder
Adewuyi EO et al. “Genetic analysis of endometriosis and depression identifies shared loci and implicates causal links with gastric mucosa abnormality.” Human Genetics 140(3):529-552 (2021)
Allele A
OR 0.03
p 1.0e-8
N 709,111
Large GWAS
multi-ancestry
household income
Hill WD et al. “Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income.” Nature Communications 10(1):5741 (2019)
Allele G
OR 0.01
p 1.0e-8
N 505,541
Large GWAS
European, NR
diet measurement, colorectal cancer
Papadimitriou N et al. “Genome-wide interaction study of dietary intake of fibre, fruits, and vegetables with risk of colorectal cancer.” Ebiomedicine 104:105146 (2024)
Allele G
OR —
p 3.0e-8
N 69,599
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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