rs16847897

This variant is located in the LRRC31 gene.

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Research that mentions this SNP (1)

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Genetic variants implicated in telomere length associated with left ventricular function in patients with hypertension and cardiac organ damage
AssociationN=1,106Matthias Huber et al.(2012)· Journal of Molecular Medicine

This association study of 1,106 hypertensive patients examined genetic variants implicated in telomere length (TL) and their relationship to left ventricular function. SNPs in BICD1 (chromosome 12p11) and near TERC (chromosome 3q26) showed significant associations with ejection fraction (EF): rs2630578 CC+CG vs GG showed -1.8% EF difference (p=0.002), rs10506083 AA+AG vs GG showed -1.6% EF difference (p=0.017), and rs10844149 AA+AG vs GG showed +1.2% EF difference (p=0.022). The BICD1 haplotype 3 was associated with -1.8% lower EF in carriers (p=0.002).

Traits studied:Hypertension with cardiac organ damageLeft ventricular ejection fractionLeft ventricular mass indexTelomere length
PubMedDOIMetascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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