rs17018667

This is a intron variant variant in the CRIM1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

neuroblastoma

Testori A et al. “Genetic Analysis in African American Children Supports Ancestry-Specific Neuroblastoma Susceptibility.” Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology 31(4):870-875 (2022)

Allele A

OR 0.89

p 6.0e-9

N 3,244

Large GWAS

African American or Afro-Caribbean

About CRIM1

This gene encodes a transmembrane protein containing six cysteine-rich repeat domains and an insulin-like growth factor-binding domain. The encoded protein may play a role in tissue development though interactions with members of the transforming growth factor beta family, such as bone morphogenetic proteins. [provided by RefSeq, Nov 2010]

View all CRIM1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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