rs17020136
This variant is located in the HEATR5B gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
QRS duration
Prins BP et al. “Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6.” Genome Biology 19(1):87 (2018)
Allele C
OR 0.34
p 1.0e-13
N 85,593
Meta-analysisLarge GWAS
multi-ancestry
Evans DS et al. “Fine-mapping, novel loci identification, and SNP association transferability in a genome-wide association study of QRS duration in African Americans.” Human Molecular Genetics 25(19):4350-4368 (2016)
Allele C
OR 0.51
p 2.0e-9
N 53,438
Large GWAS
multi-ancestry
About HEATR5B
Predicted to be involved in endocytosis; protein localization; and retrograde transport, endosome to Golgi. Located in Golgi apparatus; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
View all HEATR5B variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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