rs17142814

This is a intron variant variant in the GLCCI1 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

smoking initiation

Saunders GRB et al. Genetic diversity fuels gene discovery for tobacco and alcohol use. Nature 612(7941):720-724 (2022)
Allele G
OR 0.01
p 3.0e-10
N 3,382,012
Large GWAS
European, East Asian, Hispanic or Latin American, African unspecified

About GLCCI1

This gene encodes a protein of unknown function. Expression of this gene is induced by glucocorticoids and may be an early marker for glucocorticoid-induced apoptosis. Single nucleotide polymorphisms in this gene are associated with a decreased response to inhaled glucocorticoids in asthmatic patients. [provided by RefSeq, Feb 2012]

View all GLCCI1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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