rs17271883
This variant is located in the FUT6 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
cancer biomarker measurement
He M et al. “A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.” Gut 63(1):143-51 (2014)
Allele G
OR 0.28
p 5.0e-132
N 3,451
Large GWAS
East Asian
Jeon S et al. “Korea4K: whole genome sequences of 4,157 Koreans with 107 phenotypes derived from extensive health check-ups.” Gigascience 13 (2024)
Allele G
OR 0.40
p 6.0e-31
N 1,920
Large GWAS
East Asian
milk amount
Ambalavanan A et al. “Human milk oligosaccharides are associated with maternal genetics and respiratory health of human milk-fed children.” Nature Communications 15(1):7735 (2024)
Allele T
OR 5.87
p 4.0e-9
N 980
Small GWAS
multi-ancestry
About FUT6
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X, an E-selectin ligand. Mutations in this gene are a cause of fucosyltransferase-6 deficiency. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
View all FUT6 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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