rs17490626

GWAS Catalog Trait Associations (14)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

sortilin measurement

Allele C
OR 0.14
p 4.0e-69
N 47,745
Large GWAS
European

Thromboembolism

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.26
p 4.0e-68
N 438,632
Major Consortium StudyLarge GWAS
European

pulmonary embolism, Pulmonary Infarction

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.24
p 1.0e-26
N 628,352
Major Consortium StudyLarge GWAS
multi-ancestry

platelet endothelial aggregation receptor 1 measurement

Pietzner M et al. Mapping the proteo-genomic convergence of human diseases. Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele C
OR 0.18
p 3.0e-19
N 10,708
Large GWAS
European

drug use measurement, deep vein thrombosis

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.23
p 6.0e-18
N 400,487
Major Consortium StudyLarge GWAS
multi-ancestry

interleukin-17 receptor A measurement

Allele C
OR 0.06
p 1.0e-17
N 47,745
Large GWAS
European

proheparin-binding EGF-like growth factor level

Allele C
OR 0.07
p 4.0e-17
N 47,745
Large GWAS
European

encounter with health service

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.09
p 3.0e-16
N 441,953
Major Consortium StudyLarge GWAS
European

protein measurement

Pietzner M et al. Mapping the proteo-genomic convergence of human diseases. Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele C
OR 0.15
p 8.0e-15
N 10,708
Large GWAS
European

nectin-2 measurement

Allele C
OR 0.06
p 4.0e-13
N 47,745
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…