rs17518584

This is a intron variant variant in the CADM2 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

information processing speed

Ibrahim-Verbaas CA et al. “GWAS for executive function and processing speed suggests involvement of the CADM2 gene.” Molecular Psychiatry 21(2):189-197 (2016)

Allele T

OR 5.92

p 3.0e-9

N 33,337

Large GWAS

multi-ancestry

About CADM2

This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like domains and a cytosolic protein 4.1 binding site near the C-terminus. Proteins belonging to the protein 4.1 family crosslink spectrin and interact with other cytoskeletal proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

View all CADM2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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