rs17791208

This is a intron variant variant in the CCN3 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

blood protein amount

Emilsson V et al. Co-regulatory networks of human serum proteins link genetics to disease. Science (new York, N.y.) 361(6404):769-773 (2018)
Allele G
OR 0.24
p 1.0e-16
N 3,200
Large GWAS
European

About CCN3

The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development. [provided by RefSeq, Feb 2009]

View all CCN3 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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