rs17846866

This is a coding sequence variant variant in the ADIPOQ gene.

▶

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

BMI-adjusted adiponectin measurement

Spracklen CN et al. “Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences.” Plos Genetics 16(9):e1009019 (2020)

Allele G

OR 0.37

p 5.0e-45

N 9,262

Large GWAS

European

About ADIPOQ

This gene is expressed in adipose tissue exclusively. It encodes a protein with similarity to collagens X and VIII and complement factor C1q. The encoded protein circulates in the plasma and is involved with metabolic and hormonal processes. Mutations in this gene are associated with adiponectin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Apr 2010]

View all ADIPOQ variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Loading comments…