rs1796683

This variant is located in the CASC15 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

gut microbiome measurement, tobacco smoke exposure measurement

Stickley SA et al. Gene-by-environment interactions modulate the infant gut microbiota in asthma and atopy. The Journal of Allergy and Clinical Immunology 156(2):433-448 (2025)
Allele A
OR 0.02
p 1.0e-8
N 693
Small GWAS
multi-ancestry

About CASC15

This gene produces a long non-coding RNA that may regulate cell proliferation. This RNA is upregulated in hepatocellular carcinoma, where it is thought to function as an oncogene. However, some splice variants of this gene may function as a tumor suppressor in neuroblastoma and other tumor types. Circular RNA variants were observed at this gene. [provided by RefSeq, Dec 2017]

View all CASC15 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…