rs1800044
This is a variant in the HTR1A gene that changes a arginine to an leucine.
▶ClinVar annotation
Likely Benign★★★☆
2 submittersAbout HTR1A
This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]
View all HTR1A variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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