rs181026394
This is a protein-altering variant in the ABHD3 gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
1-myristoyl-2-linoleoyl-GPC (14:0/18:2) measurement
Yin X et al. “Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.” Nature Communications 13(1):1644 (2022)
Allele G
OR 1.14
p 3.0e-32
N 6,136
Large GWAS
European
level of Phosphatidylcholine (14:0_18:2) in blood serum
Ottensmann L et al. “Genome-wide association analysis of plasma lipidome identifies 495 genetic associations.” Nature Communications 14(1):6934 (2023)
Allele G
OR 0.88
p 7.0e-20
N 6,866
Large GWAS
European
lysophosphatidylcholine measurement
Tabassum R et al. “Genetic architecture of human plasma lipidome and its link to cardiovascular disease.” Nature Communications 10(1):4329 (2019)
Allele G
OR 1.08
p 2.0e-9
N 2,045
Large GWAS
European
About ABHD3
This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a very wide range of enzymes. The function of this protein has not been determined. [provided by RefSeq, Jul 2008]
View all ABHD3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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