rs181188704

This is a intron variant variant in the MEAF6 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

response to antihypertensive drug

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 3.09
p 4.0e-12
N 568,095
Major Consortium StudyLarge GWAS
multi-ancestry

About MEAF6

This gene encodes a nuclear protein involved in transcriptional activation. The encoded protein may form a component of several different histone acetyltransferase complexes. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

View all MEAF6 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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