rs181831514
This is a intergenic variant variant.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
bone tissue density
Surakka I et al. “MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk.” Nature Communications 11(1):4093 (2020)
Allele T
OR 0.53
p 2.0e-18
N 21,907
Large GWAS
European
otosclerosis
Rämö JT et al. “Genome-wide screen of otosclerosis in population biobanks: 27 loci and shared associations with skeletal structure.” Nature Communications 14(1):157 (2023)
Allele T
OR 12.30
p 3.0e-12
N 864,702
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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