rs183979857

This is a intron variant variant in the ICA1L gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

heel bone mineral density

Kemp JP et al. “Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis.” Nature Genetics 49(10):1468-1475 (2017)

Allele T

OR 0.19

p 6.0e-11

N 142,487

Large GWAS

European

About ICA1L

Predicted to enable protein domain specific binding activity. Predicted to be involved in regulation of transport. Predicted to act upstream of or within spermatid development. Predicted to be located in acrosomal vesicle. Predicted to be active in Golgi apparatus. [provided by Alliance of Genome Resources, Jul 2025]

View all ICA1L variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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