rs1844334

This is a intron variant variant in the CCDC141 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

glomerular filtration rate

Liu H et al. “Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease.” Nature Genetics 54(7):950-962 (2022)

Allele C

OR 7.87

p 4.0e-15

N 1,508,659

Large GWAS

multi-ancestry

Stanzick KJ et al. “Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals.” Nature Communications 12(1):4350 (2021)

Allele C

OR 0.00

p 5.0e-13

N 1,201,930

Large GWAS

multi-ancestry

About CCDC141

Predicted to be involved in brain development. Predicted to act upstream of or within centrosome localization and cerebral cortex radially oriented cell migration. Predicted to be located in centrosome and cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all CCDC141 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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