rs185857212
This is a coding sequence variant variant in the SPNS1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
level of apolipoprotein B receptor in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele A
OR 0.38
p 2.0e-20
N 47,745
Large GWAS
European
About SPNS1
Predicted to enable transmembrane transporter activity. Predicted to be involved in lysophospholipid transport and phospholipid efflux. Predicted to act upstream of or within regulation of lysosomal lumen pH. Located in lysosomal membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all SPNS1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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