rs1863622
▶GWAS Catalog Trait Associations (10)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (10)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
level of myosin regulatory light chain 2, atrial isoform in blood serum
Surapaneni A et al. “Identification of 969 protein quantitative trait loci in an African American population with kidney disease attributed to hypertension.” Kidney International 102(5):1167-1177 (2022)
Allele C
OR 0.96
p 7.0e-60
N 466
Small GWAS
African American or Afro-Caribbean
level of adhesion G-protein coupled receptor F2 in blood serum
Kuliesius J et al. “Efficient candidate drug target discovery through proteogenomics in a Scottish cohort.” Communications Biology 8(1):1300 (2025)
Allele C
OR 1.14
p 3.0e-36
N 182
Small GWAS
European
estrogen receptor measurement
Thareja G et al. “Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations.” Human Molecular Genetics 32(6):907-916 (2023)
Allele C
OR 0.37
p 1.0e-34
N 2,935
Large GWAS
Greater Middle Eastern (Middle Eastern, North African or Persian)
tumor necrosis factor receptor superfamily member 16 measurement
Allele C
OR 0.37
p 3.0e-34
N 3,301
Large GWAS
European
interleukin-22 measurement
Gudjonsson A et al. “A genome-wide association study of serum proteins reveals shared loci with common diseases.” Nature Communications 13(1):480 (2022)
Allele C
OR 0.25
p 9.0e-31
N 5,359
Large GWAS
European
soluble calcium-activated nucleotidase 1 measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele C
OR 0.07
p 2.0e-24
N 47,745
Large GWAS
European
gastrin-releasing peptide measurement
Allele C
OR 0.25
p 2.0e-16
N 3,301
Large GWAS
European
level of E3 ubiquitin-protein ligase CCNB1IP1 in blood serum
Kuliesius J et al. “Efficient candidate drug target discovery through proteogenomics in a Scottish cohort.” Communications Biology 8(1):1300 (2025)
Allele C
OR 0.81
p 1.0e-15
N 190
Small GWAS
European
kininogen-1 measurement
Thareja G et al. “Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations.” Human Molecular Genetics 32(6):907-916 (2023)
Allele C
OR 0.24
p 2.0e-14
N 2,935
Large GWAS
Greater Middle Eastern (Middle Eastern, North African or Persian)
blood protein amount
Gudjonsson A et al. “A genome-wide association study of serum proteins reveals shared loci with common diseases.” Nature Communications 13(1):480 (2022)
Allele C
OR 0.16
p 1.0e-12
N 5,362
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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