rs1868590
This is a regulatory region variant variant in the RABGAP1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
type 2 diabetes mellitus
Huerta-Chagoya A et al. “Rare variant analyses in 51,256 type 2 diabetes cases and 370,487 controls reveal the pathogenicity spectrum of monogenic diabetes genes.” Nature Genetics 56(11):2370-2379 (2024)
Allele C
OR 0.07
p 7.0e-9
N 421,743
Large GWAS
multi-ancestry
About RABGAP1
Enables GTPase activator activity and small GTPase binding activity. Located in cytosol. [provided by Alliance of Genome Resources, Jul 2025]
View all RABGAP1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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