rs1881797
This is a downstream gene variant variant in the OR2C3 gene.
▶Research that mentions this SNP (1)
▶Replication analysis confirms the association of several variants with acute myeloid leukemia in Chinese populationAssociationN=1,579Songyu Cao et al.(2016)· Journal of Cancer Research and Clinical Oncology
Replication study in a Chinese population confirming associations between 16 SNPs and acute myeloid leukemia (AML) risk identified in European GWAS studies. Seven SNPs showed significant associations with AML susceptibility, including rs2191566 (OR=1.46), rs9290663 (OR=1.26), rs11155133 (OR=1.32), rs10873876 (OR=0.62, protective), rs2239633, rs10821936, and rs2242041, in a case-control study of 545 AML cases and 1034 controls.
About OR2C3
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
View all OR2C3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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