rs188277002

This is a upstream gene variant variant in the SHE gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

mental or behavioural disorder

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele T
OR 2.78
p 1.0e-11
N 571,726
Major Consortium StudyLarge GWAS
multi-ancestry

About SHE

Predicted to enable phosphotyrosine residue binding activity. [provided by Alliance of Genome Resources, Jul 2025]

View all SHE variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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