rs188285518
This variant is located in the VPS36 gene.
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
NF-kappa-B essential modulator measurement
Kalnapenkis A et al. “Genetic determinants of plasma protein levels in the Estonian population.” Scientific Reports 14(1):7694 (2024)
Allele T
OR 1.22
p 4.0e-9
N 497
Small GWAS
European
level of integrin beta-5 in blood
Kalnapenkis A et al. “Genetic determinants of plasma protein levels in the Estonian population.” Scientific Reports 14(1):7694 (2024)
Allele T
OR 1.05
p 2.0e-8
N 488
Small GWAS
European
level of STAM-binding protein in blood
Kalnapenkis A et al. “Genetic determinants of plasma protein levels in the Estonian population.” Scientific Reports 14(1):7694 (2024)
Allele T
OR 1.21
p 2.0e-8
N 489
Small GWAS
European
level of 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial in blood
Kalnapenkis A et al. “Genetic determinants of plasma protein levels in the Estonian population.” Scientific Reports 14(1):7694 (2024)
Allele T
OR 1.21
p 4.0e-8
N 497
Small GWAS
European
About VPS36
This gene encodes a protein that is a subunit of the endosomal sorting complex required for transport II (ESCRT-II). This protein complex functions in sorting of ubiquitinated membrane proteins during endocytosis. A similar protein complex in rat is associated with RNA polymerase elongation factor II. [provided by RefSeq, Aug 2013]
View all VPS36 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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