rs1884139

This is a intron variant variant in the DDAH1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

serum dimethylarginine amount

Seppälä I et al. “Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.” European Heart Journal 35(8):524-31 (2014)

Allele T

OR 0.18

p 1.0e-18

N 5,110

Large GWAS

European

About DDAH1

This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. [provided by RefSeq, Jul 2008]

View all DDAH1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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