rs189350593
This is a regulatory region variant variant in the NAA15 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Back pain
Freidin MB et al. “Insight into the genetic architecture of back pain and its risk factors from a study of 509,000 individuals.” Pain 160(6):1361-1373 (2019)
Allele A
OR 0.13
p 4.0e-8
N 453,862
Large GWAS
European
About NAA15
N-alpha-acetylation is among the most common post-translational protein modifications in eukaryotic cells. This process involves the transfer of an acetyl group from acetyl-coenzyme A to the alpha-amino group on a nascent polypeptide and is essential for normal cell function. This gene encodes the auxillary subunit of the N-terminal acetyltransferase A (NatA) complex. [provided by RefSeq, Jan 2017]
View all NAA15 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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