rs189452885
This is a regulatory region variant variant in the GATAD2A gene.
▶GWAS Catalog Trait Associations (10)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (10)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
triacylglycerol 56:6 measurement
Ottensmann L et al. “Genome-wide association analysis of plasma lipidome identifies 495 genetic associations.” Nature Communications 14(1):6934 (2023)
Allele A
OR 0.34
p 2.0e-15
N 7,151
Large GWAS
European
triacylglycerol 50:4 measurement
Ottensmann L et al. “Genome-wide association analysis of plasma lipidome identifies 495 genetic associations.” Nature Communications 14(1):6934 (2023)
Allele A
OR 0.29
p 1.0e-11
N 7,166
Large GWAS
European
level of triacylglycerol (56:6) in blood serum
Tabassum R et al. “Lipidome- and Genome-Wide Study to Understand Sex Differences in Circulatory Lipids.” Journal of the American Heart Association 11(19):e027103 (2022)
Allele A
OR 0.36
p 4.0e-11
N 4,642
Large GWAS
European
level of Triacylglycerol (51:3) in blood serum
Ottensmann L et al. “Genome-wide association analysis of plasma lipidome identifies 495 genetic associations.” Nature Communications 14(1):6934 (2023)
Allele A
OR 0.28
p 7.0e-11
N 7,119
Large GWAS
European
triacylglycerol 52:5 measurement
Ottensmann L et al. “Genome-wide association analysis of plasma lipidome identifies 495 genetic associations.” Nature Communications 14(1):6934 (2023)
Allele A
OR 0.28
p 8.0e-11
N 7,172
Large GWAS
European
triacylglycerol 50:3 measurement
Ottensmann L et al. “Genome-wide association analysis of plasma lipidome identifies 495 genetic associations.” Nature Communications 14(1):6934 (2023)
Allele A
OR 0.28
p 9.0e-11
N 7,161
Large GWAS
European
level of Triacylglycerol (49:2) in blood serum
Ottensmann L et al. “Genome-wide association analysis of plasma lipidome identifies 495 genetic associations.” Nature Communications 14(1):6934 (2023)
Allele A
OR 0.28
p 1.0e-9
N 6,076
Large GWAS
European
level of Phosphatidylcholine (18:1_20:4) in blood serum
Tabassum R et al. “Lipidome- and Genome-Wide Study to Understand Sex Differences in Circulatory Lipids.” Journal of the American Heart Association 11(19):e027103 (2022)
Allele A
OR 0.41
p 1.0e-8
N 2,624
Large GWAS
European
triacylglycerol 52:4 measurement
Ottensmann L et al. “Genome-wide association analysis of plasma lipidome identifies 495 genetic associations.” Nature Communications 14(1):6934 (2023)
Allele A
OR 0.24
p 1.0e-8
N 7,174
Large GWAS
European
triacylglycerol 56:7 measurement
Tabassum R et al. “Lipidome- and Genome-Wide Study to Understand Sex Differences in Circulatory Lipids.” Journal of the American Heart Association 11(19):e027103 (2022)
Allele A
OR 0.31
p 2.0e-8
N 4,642
Large GWAS
European
About GATAD2A
Enables protein-macromolecule adaptor activity. Involved in chromatin remodeling and negative regulation of DNA-templated transcription. Located in nucleoplasm. Part of NuRD complex. [provided by Alliance of Genome Resources, Jul 2025]
View all GATAD2A variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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