rs189464266

This is a upstream gene variant variant in the KLF17 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

corneal neovascularization

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 2.93
p 4.0e-11
N 625,667
Major Consortium StudyLarge GWAS
multi-ancestry

About KLF17

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within gamete generation. Predicted to be located in chromatin. [provided by Alliance of Genome Resources, Jul 2025]

View all KLF17 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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