rs1899132

This is a intron variant variant in the PPM1K-DT gene.

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

3-methyl-2-oxobutyrate measurement

Yin X et al. “Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.” Nature Communications 13(1):1644 (2022)

Allele A

OR 0.19

p 2.0e-25

N 6,136

Large GWAS

European

4-methyl-2-oxopentanoate measurement

Yin X et al. “Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.” Nature Communications 13(1):1644 (2022)

Allele A

OR 0.17

p 4.0e-21

N 6,136

Large GWAS

European

3-methyl-2-oxovalerate measurement

Yin X et al. “Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.” Nature Communications 13(1):1644 (2022)

Allele A

OR 0.15

p 3.0e-17

N 6,136

Large GWAS

European

valine measurement

Yin X et al. “Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.” Nature Communications 13(1):1644 (2022)

Allele A

OR 0.14

p 1.0e-13

N 6,136

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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