rs190985523

This is a regulatory region variant variant in the SLAMF7 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

CD48 antigen measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele A

OR 0.71

p 7.0e-18

N 47,745

Large GWAS

European

About SLAMF7

Enables identical protein binding activity. Predicted to be involved in T cell activation and immune response. Predicted to act upstream of or within regulation of natural killer cell activation. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Jul 2025]

View all SLAMF7 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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