rs192024599

This is a intron variant variant in the SYS1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

amount of WAP four-disulfide core domain protein 12 (human) in blood

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele A

OR 0.46

p 7.0e-53

N 47,745

Large GWAS

European

About SYS1

SYS1 forms a complex with ADP-ribosylation factor-related protein ARFRP1 (MIM 604699) and targets ARFRP1 to the Golgi apparatus (Behnia et al., 2004 [PubMed 15077113]).[supplied by OMIM, Aug 2009]

View all SYS1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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