rs192247958

This is a intron variant variant in the FCHO2 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

brain cancer

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 3.77
p 3.0e-12
N 572,159
Major Consortium StudyLarge GWAS
multi-ancestry

About FCHO2

Enables identical protein binding activity. Involved in clathrin coat assembly and clathrin-dependent endocytosis. Located in clathrin-coated pit and clathrin-coated vesicle. [provided by Alliance of Genome Resources, Jul 2025]

View all FCHO2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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